Upstream Pharmaceuticals, LLC

Upstream Pharmaceuticals, LLC is a wholesale drug distributor based in Plano, TX, with FDA registration and clean regulatory history but significant licensing gaps—only 9 of its 28 state licenses remain active, with 19 expired across its 28-state footprint. While the company maintains DSCSA compliance and has no FDA recalls or warning letters on record, it lacks both NABP accreditation and DEA registration, which may limit its ability to distribute controlled substances and could signal operational or administrative challenges in maintaining its broader licensing portfolio.